Tablet and capsule pharmaceutical horizontal mixer is a horizontal mixer specially designed for the pharmaceutical industry. It is designed with a U-shaped cylinder and precision paddles to achieve 99%+ uniform mixing of pharmaceutical ingredients. The 316L stainless steel fully enclosed body is mirror polished with Ra≤0.8μm, strictly in line with GMP certification standards. From small-batch trial production in the laboratory to large-scale industrial production, the intelligent PLC control system accurately controls the speed and time to ensure the stability of the pharmaceutical ingredients in each batch. It is the core tool for quality control of tablet and capsule production.
The tablet and capsule pharmaceutical horizontal mixer has many significant advantages in pharmaceutical production.
Shorten process time: The unique stirring mechanism and movement mode can quickly achieve uniform mixing of materials, significantly shorten the production cycle, and improve production efficiency.
High mixing degree ensures drug quality: It can achieve full mixing of materials in three-dimensional space, reduce mixing dead corners, ensure the uniformity of drug ingredients between batches, and ensure the stability and reliability of drug quality.
Gentle mixing protects drug activity: Compared with high-shear mixing equipment, horizontal mixers usually use a gentler mixing method to reduce the risk of damage to active pharmaceutical ingredients, especially for shear-sensitive materials.
Closed operation meets GMP requirements: The fully enclosed structure effectively prevents dust and external pollution, meeting the pharmaceutical industry's strict requirements for a clean production environment.
Wide range of applications: By adjusting the mixing mechanism and operating parameters, it can meet the mixing needs of powdered or granular materials of different properties and particle sizes.
High degree of customization: Manufacturers can usually customize the design according to the customer's special process requirements, such as adding a spray system, heating/cooling jacket, sampling port, etc.
The equipment adopts a fully enclosed structure to prevent cross contamination. Its core structures are mainly the following.
Main structure: It adopts a U-shaped horizontal cylinder design. The parts in contact with the material are made of food-grade 316L stainless steel. There is a quick-opening feeding port on the top of the cylinder and a pneumatic discharge valve at the bottom.
Mixing system: The core mixing shaft runs through the center of the cylinder, and different types of blades can be equipped according to the characteristics of the material.
Transmission and control system: The transmission system consists of a variable frequency motor, a reducer and a coupling, and supports 0-100rpm stepless speed regulation to meet the mixing requirements of different materials and different processes.
When the material enters the U-shaped cylinder, the mixing shaft drives the blades to rotate at high speed, producing a three-dimensional mixing effect: in the axial direction, the spiral blades push the material to circulate along both ends of the cylinder; in the radial direction, the rotation of the blades causes the material to roll and diffuse; at the same time, the material is constantly thrown up and down under the action of centrifugal force, forming a staggered blend. Materials of different densities and particle sizes are repeatedly convection, shear and diffusion to achieve uniform mixing from local to overall.
Designed for mixing tablet excipients, capsule contents, etc., it is suitable for R&D laboratories and industrial mass production. It is the core equipment for solid preparation production!
Tablet production: The horizontal mixer fully mixes the active ingredients of the drug, fillers (such as starch, lactose), adhesives, lubricants, etc. according to the prescription ratio to ensure the consistency of material fluidity and compressibility.
Capsule filling: The horizontal mixer can accurately control the particle size and uniformity of the material, avoid stratification, ensure that the difference in the amount of each capsule is in line with the pharmacopoeia, and ensure the synergistic effect of multiple ingredients in the compound capsule.
Capsule powder production: When mixing the powder, extract and excipients in the capsule, the problem of high viscosity and complex ingredients of Chinese medicine materials can be effectively solved by optimizing the blade structure and mixing process.
Health care product production: It is suitable for the production of health care products such as vitamin tablets, probiotic capsules, dietary supplements, etc., to ensure uniform distribution of nutrients and improve product quality and market competitiveness.
|
odel |
LHY-0.25 |
LHY-0.5 |
LHY-1 |
LHY-1.5 |
LHY-2 |
LHY-3 |
LHY-4 |
LHY-6 |
LHY-8 |
LHY-10 |
|
One-time mixing (kg) |
100-150 |
200-300 |
400-600 |
600-900 |
800-1000 |
1200-1800 |
1600-2400 |
2400-3600 |
3200-4800 |
4000-6000 |
|
Mixing time (min) |
8-20 |
8-20 |
8-20 |
8-20 |
8-20 |
8-20 |
8-20 |
8-20 |
8-20 |
8-20 |
|
Mixing speed (r/min) |
60 |
55 |
45 |
40 |
35 |
25 |
25 |
20 |
15 |
15 |
|
Motor power (kw) |
3-5.5 |
4-11 |
7.5-15 |
11-18.5 |
15-22 |
18.5-30 |
22-37 |
37-55 |
37-55 |
45-75 |
|
Weight (kg) |
500 |
900 |
1800 |
2500 |
3200 |
4100 |
5100 |
6300 |
7500 |
|
Our equipment has served more than 100 pharmaceutical companies, increasing production capacity by 30-50%. See how actual cases solve pharmaceutical problems such as uneven mixing and cross contamination!
Large pharmaceutical company: When producing a cardiovascular tablet, the original mixing equipment had insufficient mixing uniformity, resulting in an 8% drug content failure rate. After introducing our 500L horizontal mixer, the mixing uniformity was improved to 99.3% by optimizing the blade angle and mixing parameters, and the product failure rate was reduced to less than 1%.
Chinese medicine preparation company: In the process of producing compound Chinese medicine capsules, the material was faced with problems of high viscosity and severe stratification. After customizing a 200L horizontal mixer with plow blades and anti-stick coating, the mixing time was shortened from 15 minutes to 6 minutes, and the production efficiency was increased by 150%.
International health care product company: In order to meet the production needs of high-end probiotic capsules, our 1000L explosion-proof horizontal mixer was purchased, equipped with vacuum degassing and low-temperature temperature control functions to effectively protect the activity of probiotics.
Focus on pharmaceutical needs! A large-scale analysis of the selection points will help you lock in efficient, compliant and precise mixing equipment to lay a solid foundation for drug quality.
Capacity demand assessment: Select equipment with appropriate volume according to the company's annual output and batch size. It is recommended to reserve 20%-30% of capacity redundancy to avoid overload of equipment.
Material property analysis: Clarify the particle size, density, fluidity, heat sensitivity, viscosity and other characteristics of the material, and select the appropriate blade type and equipment configuration. For example, when handling highly viscous materials, anti-stick coating and strong stirring blades are required; when handling heat-sensitive materials, a jacket temperature control system needs to be installed.
Demand for intelligence: According to the company's digital transformation plan, select equipment with functions such as data collection, remote monitoring, and process parameter memory to improve production management efficiency and quality traceability.
The price of tablet and capsule pharmaceutical horizontal mixer is affected by multiple factors and needs to be comprehensively evaluated in combination with equipment configuration and production needs. Equipment volume is the core variable. From small laboratory models to large industrial-grade equipment, the difference in specifications will be directly reflected in the cost. In terms of intelligence, the price range of basic manually operated equipment and high-end models equipped with PLC control systems and data traceability functions is relatively wide. In addition, customized designs for special materials, such as anti-stick coatings, explosion-proof structures, temperature control systems, etc., will also increase costs accordingly. For specific detailed model price lists, please contact us directly, and we will make a detailed price list exclusively for you!
Tablet and capsule pharmaceutical horizontal mixers have become the core equipment for pharmaceutical companies to improve product quality and optimize production efficiency with their scientific design, excellent performance and wide applicability. With the continuous improvement of the pharmaceutical industry's requirements for drug quality and production efficiency, horizontal mixers will continue to innovate and upgrade, and provide stronger support for the high-quality development of the pharmaceutical industry through the application of intelligent and automated technologies.
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