Pharmaceutical ribbon blender is designed for the pharmaceutical industry and is made of 316L stainless steel with a polished surface that complies with GMP standards. The equipment achieves high-precision mixing with a CV value of ≤5% through the convection and shearing motion of the double ribbons. The uniformity is far superior to that of traditional equipment. It is widely used in the production of solid preparations, ointments and other drugs, and is a key device to ensure the quality of drugs.
In the pharmaceutical industry, ribbon mixing equipment is widely used for mixing powders, particles or high-viscosity materials due to its high-speed mixing, heat transfer and gentle handling characteristics. Different types of ribbon mixing have their own characteristics.
Horizontal stainless steel ribbon mixer: It adopts a horizontal barrel design and is equipped with a reverse spiral ribbon inside. It is suitable for mixing high-viscosity materials (such as ointments and ointments). It has a high degree of mixing uniformity and can be used with a jacket for heating or cooling. Its advantage is that it has a strong ability to handle viscous materials.
Vertical stainless steel ribbon blender: The vertical structure saves space, and the vertical mixing is combined with the lifting mechanism. It is suitable for the gentle mixing of powders (such as antibiotics, vitamins) and low-density materials, reducing particle breakage. The bottom discharge design reduces residues and is easy to clean. It is suitable for powder homogenization and API mixing.
V-shaped stainless steel ribbon blender: Through the synergistic effect of container rotation and internal ribbon, high-speed, no-dead-angle mixing of powders with good fluidity is achieved. It is easy to clean and suitable for frequent material changes.
Professional pharmaceutical-grade ribbon blender, made of 316L stainless steel, meets GMP standards, and achieves efficient and uniform mixing.
High-precision mixing: The double-helix reverse motion technology is used to achieve synchronous axial and radial flow of materials, and the mixing uniformity CV value is ≤5%, far exceeding traditional mixing equipment.
Flexible adaptation to complex material requirements: With strong material handling capabilities, it can stably mix high-viscosity materials such as syrups and gel matrices with a viscosity of up to 500Pa・s; it supports solid-liquid mixing with a solid particle ratio of ≤60%, effectively preventing agglomeration.
Strictly abide by clean production standards: fully guarantee production safety and hygiene, support CIP online cleaning and SIP online sterilization, and eliminate cross contamination; the scraper device is combined with the polished inner wall to control the discharge residue to ≤0.1%
Explosion-proof system: It also provides optional configurations such as explosion-proof motors and electrostatic grounding to build a solid safety line for production scenarios using flammable and explosive solvents.
Customization: The product height and processing port position can be changed according to the customer's on-site conditions.
The pharmaceutical ribbon blender drives high-viscosity or high-solid content materials to form a three-dimensional convection cycle in the tank through the relative rotation of double-layer spiral blades (outer layer clockwise, inner layer counterclockwise) - the outer spiral pushes the material from the tank wall to the center, and the inner spiral reverses to both sides, so that the material continues to roll, shear and diffuse under low shear force, and finally achieves uniform mixing.
The ribbon mixer designed for the pharmaceutical industry is made of 316L stainless steel and meets GMP standards. It is suitable for uniform mixing of ointments, powders, APIs and other materials.
Production of solid preparations: In the production of solid preparations such as tablets, capsules, and granules, the medical ribbon mixer can fully mix the active ingredients of the drug with various excipients to ensure uniform distribution of the drug ingredients.
Production of semi-solid preparations: For semi-solid preparations such as ointments, creams, and gels, the mixer can evenly mix drugs, matrices, additives, etc., so that the product texture is fine and uniform without stratification.
Production of liquid preparations: In the production of liquid preparations such as oral liquids and syrups, the medical ribbon mixer can evenly mix drugs, solvents, flavoring agents, preservatives, etc. to ensure that the taste and efficacy of each bottle of product are consistent.
Production of Chinese medicine preparations: In the production process of Chinese medicine pills, powders, ointments, etc., the mixer can mix Chinese herbal medicine powders, extracts, excipients, etc. according to the formula ratio to ensure that the Chinese medicine ingredients are uniform and the efficacy is fully exerted.
Special pharmaceutical product production: For special pharmaceutical products such as vaccines, blood products, and biologics, pharmaceutical ribbon mixers can be customized to meet their strict production process requirements.
The pharmaceutical grade uses 316L stainless steel, complies with GMP certification, supports CIP/SIP cleaning, and mixes more evenly; the ordinary type is mostly 304 stainless steel, with a simple structure and suitable for general industry.
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Comparison Item |
Medical Ribbon Mixer |
Ordinary Belt Mixer |
|
Material |
316L stainless steel, surface polished, corrosion-resistant and easy to clean |
304 stainless steel or carbon steel, rough surface treatment |
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Hygienic Design |
Dead-angle-free, compatible with CIP/SIP cleaning, sealed for dust and contamination prevention |
Simple structure, potential residual dead angles, difficult for thorough cleaning |
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Mixing Method |
Ribbon + convection + shearing, more uniform mixing, suitable for high-viscosity materials |
Ordinary belt stirring, lower mixing efficiency, suitable for low-viscosity materials |
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Temperature Control |
Optional jacket heating/cooling, suitable for pharmaceutical process requirements |
Usually no temperature control system, or only basic heating |
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Sealability |
Explosion-proof, nitrogen protection, suitable for aseptic or API mixing |
Ordinary seal, unsuitable for high-demand dust-proof/explosion-proof environments |
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Speed Control |
Frequency conversion speed regulation, low-speed start to avoid damaging sensitive materials |
Fixed speed or simple speed regulation, may affect material integrity |
The pharmaceutical grade ribbon mixers we provide strictly follow the following international and industry standards to ensure that the equipment meets the stringent requirements of pharmaceutical production.
Material standards: The parts of the pharmaceutical grade ribbon mixer that come into contact with the material are made of 316L stainless steel, and the surface is mirror polished to ensure that there are no sanitary dead corners.
Design and manufacturing standards: The equipment strictly follows the China-EU standards and provides complete verification document support. The fully enclosed structure and quick-release interface design effectively avoid cross contamination and support CIP/SIP online cleaning and sterilization.
Safety standards: Explosion-proof certification, suitable for flammable and explosive environments; electrical system complies with CE standards and IP65 protection level.
Customized service: Supports extended certification according to customer needs. All equipment is strictly tested before leaving the factory, and is accompanied by material certification, compliance certificate and complete verification documents, providing pharmaceutical companies with full-cycle compliance guarantees from selection to acceptance.
In order to meet diverse process requirements, we provide a series of customized solutions.
Liquid spray system: Used to add trace liquids (such as adhesives, flavors, nutrient solutions) to powders, and atomize them evenly.
Jacket temperature control system: Can be connected to steam, heat transfer oil or cooling water to achieve heating, drying or cooling of materials.
Vacuum system: Used for vacuum feeding, vacuum mixing or vacuum drying of materials to prevent oxidation.
Explosion-proof configuration: For flammable and explosive dust environments, provide complete machine designs that meet ATEX or Chinese explosion-proof standards.
Integration of supporting equipment: We provide seamless connection with upstream and downstream equipment such as vacuum feeders, dust-free feeding stations, ton bag packaging machines, rotary vibrating screens, conveyors, etc., to build a fully automatic and dust-free production line.
Dahan Machinery's products strictly comply with GMP and FDA certification standards. The company uses 316L stainless steel and precision polishing technology to ensure that the equipment has no sanitary dead corners, and supports CIP/SIP cleaning to meet aseptic production requirements. Provide horizontal, vertical, V-shaped and other structures of spiral ribbon mixers, suitable for ointments, powders, API mixing and other pharmaceutical processes, and can customize jacket temperature control, explosion-proof sealing and inert gas protection functions. With the advantages of efficient mixing, low shear and easy cleaning, the products are widely used in the fields of pharmaceuticals, bioengineering and food. We are committed to providing customers with one-stop solutions from equipment selection to after-sales support, helping pharmaceutical production to operate efficiently and compliantly.
With its excellent mixing performance and process adaptability, pharmaceutical spiral ribbon mixers have become an important tool for pharmaceutical companies to enhance their competitiveness.
Address:China,Yanjin county forest park gate to the west 1000 meters north road.
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